Vitamin B1

Legal Number

(CAS RN) : 59-43-8

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Molecular

Formula: C₁₂H₁₇CIN₄OS

Weight: 300.81

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Easy to decompose metamorphoism in alkaline solution. Ph 3.5 to 100^oC high temperature resistantm, acid and alkali easy failure is greater than 5. Light and heat titer decreased. Reason should be placed in the window, cool, preservation,

storage should be placed in the window, cool, preservation, storage shoulds not be long. In acidic, solution is stable, in the alkaline solution is not stable, susceptible to oxidation and heat damage. Reducing substances sulfite, such as sulfur dioxide can make vitamin B1 inactivation.

 

Widely distributed in the skeletal muscle, cardiac muscle, liver, kidney and brain tissue, has a half-life of 9 ~ 10 days. Vitamin B1 mainly exists in the outside of the seed and germs, such as rice bran and bran is rich in content, content is extremely rich in yeast. Lean meat, Chinese

cabbage and celery also relatively rich in content. Vitamin B1 is used in the chemical synthesis of products. In the body, vitamin B1 in the form of coenzyme involved in the catabolism of sugar, protect the role of the nervous system; Also can promote gastrointestinal peristalsis, increase appetite.

 

Vitamin B1 deficiency, can cause a variety of nerve inflammation, such as beriberi. Vitamin B1 deficiency caused by multiple neuritis, in patients with peripheral nerve endings have inflammation and degeneration phenomenon, accompanied by numbness of limbs, muscle contraction, heart

failure, lower limb swelling and other symptoms. Beriberi 18~19 century in China, Japan is particularly popular in southeast Asia area, at the time about hundreds, thousands of die each year from beriberi. Earlier treatment with beriberi in ancient Chinese medical books, Chinese famous doctor

Sun Simiao known treatment with husk beriberi. In modern, medicine, Vitamin B1 treatment of beriberi and  various nerve inflammation has significant curative effect.

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